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Prescol 200mg 30 Tabs, Trimebutine

Prescol 200mg 30 Tabs, Trimebutine
Current Reviews:0

Prescol 200mg 30 Tabs, Trimebutine

Trimebutine maleate 200 mg
Excipient c.b.p. 1 tablet .
INDICATIONS: Libertrim ® Tablets and capsulets Libertrim ® Tablets are mainly pitch and regular action gastroesophageal and intestinal motility . They are particularly indicated in the treatment of irritable bowel syndrome (IBS ) , and relieving the symptoms that characterize this condition such as cramping abdominal pain , constipation and / or diarrhea , abdominal distention , bloating , flatulence .
Libertrim ® Tablets and capsulets Libertrim ® Tablets are also indicated in acute and chronic colitis, spastic colitis, functional colopathies , reflux esophagitis, duodenitis and other pathologies that course with alterations of tone and motility and gastro- intestinal .
Pharmacokinetics HUMAN : Trimebutine of Libertrim ® is well absorbed from the gastrointestinal tract, with peak plasma levels (Cmax ) in 1-2 hours.
Trimebutine removal is rapid , primarily in the urine : 70 % at about 24 hours.
Trimebutine performs its spasmolytic effects , musculotropic by having a similar chemical structure to acetylcholine , so they have a regulating effect on intestinal smooth muscle and acts on substrate competition with acetylcholine , in the digestive tract . Deals mainly fiber disturbed nerve ganglia in the myenteric plexus of Auerbach and the submucosal plexus of Meissner , allowing acetylcholine and adrenaline acting on the periphery.
Antiinflammatory action itself is effected trimebutine through an indirect path which causes vasoconstriction when in contact with mucous , leading to the vessels in the submucosa regain normal size.
Trimebutine acts as an analgesic on the spinal and mesencephalic transmissions because they performed a selection of messages along the path of the roads that lead to the bulbar and hypothalamic centers , has no effect on the waking state , on the activity driving and thermoregulation. Furthermore, peripheral Enkephalinergic interacts with receptors , responsible for the modulation of peristalsis in the intestinal tract .
Hypersensitivity to the active substance .
PRECAUTIONS: In therapeutic use , despite the high safety margin of the drug , it is recommended to respect the suggested dose in the dosage schedule and that it has been widely proven clinical efficacy of the drug.
RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION : Laboratory studies in several animal species have confirmed that Libertrim ® Trimebutine no teratogenic or fetotoxic effects , however , their use during the first trimester of pregnancy is under the discretion of the physician .
ADVERSE REACTIONS : In most cases Trimebutine Libertrim ® has excellent tolerability , only rarely been reported headache or mild skin reactions, which have not required discontinuation of therapy .
The Libertrim ® trimebutine has high clinical , hematic and renal tolerability , allowing it to be used for long periods and that the dose should be increased according to the requirements of the case and the physician's discretion , without risk of adverse effects that frequently occur with the use of anticholinergic antispasmodics or calcium antagonists (intestinal paralysis ; constipation ± constipation, dry mouth, blurred vision , urinary retention, drowsiness).
In addition , no adverse effects of anticholinergic , central or peripheral type , and may be administered to patients enrolled with ileus , glaucoma , cardiovascular disorders , pyloric or prostatic hypertrophy, and even alcohol poisoning alcohol detoxification therapy .
DRUG INTERACTIONS : Studies and clinical experience with the use of Trimebutine Libertrim ® show that a drug is provided with wide tolerance and is compatible with antibiotics , antimicrobials, anti-amoebic , antiparasitic , NSAIDs, ataraxics , tranquilizers , hypnotics antagonists of histamine H2 receptors , hypoglycemic , antihypertensive , antiarrhythmic , anticoagulant , antiplatelet , and peripheral vasodilators cerebales , B, multivitamins and food supplements remineralizantes complex .
There are no reports to date of inconsistency Libertrim ® Trimebutine orally administered with other drugs or alcohol, or other kind of interactions. Nor cause loss of appetite or refusal to formula in infants when administered along with it.
The sucrose content of the vehicle in the condition of the diabetic metabolic rate must be considered.
PRECAUTIONS IN RELATION TO EFFECTS Carcinogenesis, Mutagenesis , Impairment of Fertility Studies in animals have not shown risk mutagenic or teratogenic nor carcinogenic . Moreover, in this regard, human , no case reports in the international and national literature.
Libertrim ® Tablets 100 mg :
Teens : 1 tablet every 8 hours.
Adults: 1-2 tablets every 8 hours.
Capsulets Libertrim ® Tablets 200 mg :
Teens : capsulets  ½ tablet every 8 hours.
Adults: 1 tablet capsulets every 8 or 12 hours.
We recommend taking the drug 15 to 30 minutes before meals , for a minimum period of 4-8 weeks at physician discretion.
MANIFESTATIONS AND MANAGEMENT OF OVERDOSE OR ACCIDENTAL INGESTION : A recommended doses have not been reported problems of intoxication, nor are there reports of toxicity caused by overdose.
Libertrim ® has high clinical tolerance , renal hematic and allowing it to be used for prolonged periods and increasing doses , depending on the requirements of the case, without the occurrence of adverse effects or toxicity .
Libertrim ® Tablets 100 mg : Box of 20
and 50 tablets in blister pack .
Capsulets Libertrim ® Tablets 200 mg : Box of 24, 48 , 60 and 90 tablets in blister pack .
RECOMMENDED STORAGE : Store at room temperature to no more than 30 ° C in a dry temperature.
  • Drug Name: PRESCOL
  • Comparable patent medicine: Libertrim
  • Active Ingredients: Trimebutine
  • Presentation: Capsules
  • Concentration: 200MG
  • Extended-release tablets: No
  • Lab: Carnot, SA de C.V.
  • 48comprimidos box
  • Made in Mexico

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