Keflex 500mg 20 Tabs, Cephalexin
Cephalexin is indicated for the treatment of the following infections caused by susceptible strains of designated microorganisms:
· Bacterial sinusitis caused by streptococci, S. pneumoniae and Staphylococcus aureus (one methicillin susceptible strains). Respiratory tract infections caused by S. S. pneumoniaepyogenes (Penicillin is usually the antibiotic of choice in the treatment and prevention of streptococcal infections, including prophylaxis of rheumatic fever. Cephalexin is generally effective in the eradication of streptococci from the nasopharynx, but not currently There are substantial data establishing the efficacy of cephalexin in the subsequent prevention of rheumatic fever or acute bacterial endocarditis).
· Otitis media caused by S. pneumoniae, H. influenzae, staphylococci, streptococci and M.catarrhalis.
· Infection of skin and soft tissue infections caused by staphylococci and / or streptococci.
· Infection of bones and joints caused by staphylococci and / or P. mirabilis.
· Infection of the genitourinary system, including acute prostatitis, caused by E. coli, P.pneumniae mirabilis and Klebsiella.
· Infection teeth caused by staphylococci and / or streptococci.
Note: You must make the cultivation and susceptibility studies adequately before and during treatment to determine the susceptibility of pathogenic microorganisms to cephalexin. When indicated, should be made renal function studies.
Before initiation of therapy with cephalosporins, it should be a thorough investigation concerning previous hypersensitivity reactions to cephalosporins, penicillin and other drugs.The cephalosporins are contraindicated in patients with a history of allergic reactions to cephalosporin antibiotics. There are clinical and laboratory evidence of partial cross-sensitivity between β-lactam antibiotics bicyclic including penicillins, cephalosporins, cephamycins, and carbapenems. It seems to be little cross-sensitivity between antibiotics and bicyclic monobactams (eg aztreonam) of β-lactam. Although the true incidence of cross-sensitivity between β-lactam antibiotics has not been definitively established, it has been clearly documented and can occur in up to 10 to 15% of patients with a history of hypersensitivity to penicillin.
Some patients have had severe reactions, including anaphylaxis, to penicillins and cephalosporins. Cephalosporins should be used with caution in individuals hypersensitive to penicillins. Some clinicians suggest that cephalosporins be avoided in patients who have had an immediate type of reaction (anaphylactic) hypersensitivity to penicillins and should be administered with caution to patients who have had a type-delay (eg, rash, fever , eosinophilia) reaction to penicillins or other drugs. If an allergic reaction occurs during a therapy with cephalosporins, the drug should be discontinued and the patient treated with appropriate therapy (eg, epinephrine, corticosteroids, and maintenance of the airway and adequate oxygen) as indicated. Prolonged use of a cephalosporin can lead to overgrowth of nonsusceptible organisms, particularly Enterobacteriaceae, Pseudomonas, enterococci, or Candida. If superinfection occurs, appropriate therapy should be instituted. Cephalosporins should be used with caution in patients with a history of gastrointestinal disease, particularly colitis. Because the diarrhea associated with C. difficile and colitis.
DOSAGE AND ADMINISTRATION:
Cephalexin is administered orally.
Adults: The adult dosage ranges from 1 to 4 g per day in divided doses. The usual adult dose is 250 mg every 6 hours. For the following infections may be given a dose of 500 mg every 12 hours if the patient is over 15 years: strep throat, infections of the skin and soft tissue infections and uncomplicated cristitis.
In cystitis treatment should be continued for 7 to 14 days. In more severe infections or those caused by less susceptible organisms, larger doses may be required. When required daily doses greater than 4 g of cephalexin should consider giving some of the appropriate dose injectable cephalosporins.
Children: The usual recommended dose for children is 25 to 50 mg / kg body weight per day in divided doses. The total daily dose may be fractionated and administered every 12 hours in streptococcal pharyngitis in children over one years old, minor infections and uncomplicated urinary tract infections and skin and soft tissue.
In severe infections, the dose may be doubled.
In the treatment of otitis media, clinical studies have demonstrated the need to administer a dose of 75 to 100 mg / kg body weight per day in 4 divided doses.
In streptococcal infections β-hemolytic, administer a therapeutic dose of cephalexin for at least 10 days.
Drug Name: Cefalver
Comparable drug patent: Cefalver
Active substance: Cephalexin
Presentation: Oral Suspension
Extended-release tablets: No
Laboratory Maver, SA de CV
Box with bottle with powder for 90ml
And as dosing
Made in Mexico