Anapenil 400,000U SUSP INY 2ml, Penicillin, Clemizol, Benzylpenicillin
Penicillin clemizole / Benzylpenicillin SODIUM
THERAPEUTIC INDICATIONS: tonsillitis, erysipelas, scarlet fever, infections Upper Respiratory, Skin and Soft Tissue. Pneumonia and bronchopneumonia. Vincent's angina. Syphilis and gonorrhea. Is the drug of choice for eradication of GABHS in the Treatment and Prevention of rheumatic fever.
Pharmacokinetics in Humans:
ANAPENIL * inhibits the synthesis of bacterial Cell Wall exert bactericidal About MICRO sensitive. Its spectrum of activity is exercised with Most Effective against gram-positive cocci, staphylococci As penicillinase producers, streptococci of groups A, B, C, G, H, L, M and pneumococcus.
Other sensitive MICRO to Action ANAPENIL * son, Neisseria gonorrhoeae, Treponema pallidum, Corynebacterium diphtheriae, Bacillus anthracis, Clostridium, Actinomyces bovis, Streptobacillus moniliformis, Listeria and Leptospira.
The clemizol Penicillin is the result of the union of penicillin G with clemizol, Substance with antihistamine properties, which the uniRSE to penicillin, given a prolonged THIS void similar to that achieved with procaine, But Without The danger of Allergy anaphylaxis or procaine I entails.
Crystalline penicillin G sodium itself rapidly absorbed, peak serum concentrations Reaching 15 to 30 minutes after intramuscular administration do. Penicillin G clemizol itself slowly released from intramuscular Site Application, causing Constants serum levels of penicillin G During 12-24 hours. Approximate 60% of penicillin G SE bound to plasma proteins, yes distributes widely For All Fabrics And yes elimination portion tubular secretion.
Contraindications: hypersensitivity to components of the formula. The Product contains penicillin and clemizol, so patients with a history of allergy THESE substances should not receive ANAPENIL *. Also, THERE Clinical and laboratory partial cross-allergy compa penicillins and other beta-lactam antibiotics, including aminopenicillins (ampicillin and amoxicillin), carboxypenicillins (carbenicillin, ticarcillin), acilureidopenicilinas, cephalosporins, cephamycins, monobactam (aztreonam) AND EVIDENCE carbapenems (imipenem) .
PRECAUTIONS: EVIDENCE Clinical and laboratory partial cross-allergy compa penicillins and other beta-lactam antibiotics, including aminopenicillins (ampicillin, amoxicillin), carboxypenicillins (carbenicillin, ticarcillin), acilureidopenicilinas, cephalosporins, cephamycins, monobactam (aztreonam) and carbapenems (imipenem ).
Restrictions Use in Pregnancy and Lactation: No Evidence THERE adequate and Controlled studies using penicillin in Pregnant Women, For What the drug should be used during pregnancy only if the benefits justify the potential risks.
Adverse Reactions: The intramuscular administration of penicillins associates itself often a pain in the site of the Application. Like other beta-lactams, there may be allergic or hypersensitivity reactions, including skin rash, urticaria, erythema multiforme, exfoliative dermatitis, anaphylaxis, angioedema, bronchospasm, laryngospasm and hypotension.
If a severe hypersensitivity reaction occurs during therapy with penicillin, the drug should be discontinued IMMEDIATELY and install the appropriate therapy.
DRUG INTERACTIONS AND OTHER GENDER: Urinary excretion of penicillins decreases when using probenecid by also serum levels ANAPENIL * 400 and 1000 other prolong and increase with esta substance.
Alterations IN THE LABORATORY TEST RESULTS: No Have you detected.
PRECAUTIONS IN RELATION TO EFFECTS OF Carcinogenesis, Mutagenesis, Impairment of Fertility: Penicillin should be used with caution in individuals with a history of allergies. ANAPENIL * 400 and 1000 has shown no teratogenic, mutagenic, carcinogenic or Have Effects on Fertility service.
DOSAGE AND ADMINISTRATION: The suspension itself obtained by mixing the contents of the vial into the vial. The bottle should be shaken before use those. It is administered by intramuscular, Content UN bottle every 12 or 24 hours for 10 days in infections caused hemolytic streptococcus portion of Group A. In other infectious diseases DURATION depend on the etiology and Evolution of Self.
Manifestations AND MANAGEMENT OF OVERDOSE OR ACCIDENTAL intake: The toxicity of penicillins is MINIMUM. There has been informed regarding the presence of overdose cases with this Product.
ANAPENIL * 400: An ampoule bottle and vial with THINNER.
ANAPENIL * 1000: An ampoule bottle and vial with THINNER.
Customer Recommendations STORAGE: Store in a cool place.
LEGENDS OF PROTECTION:
There is Let the Scope of Children. Its sale requires medical prescription. Exclusive Medical Literature paragraph.
LABORATORIES GROSSMAN, S. A.
Drug Name: Anapenil
Comparable drug patent: Anapenil
Active substance: Penicillin clemizole / Benzylpenicillin SODIUM
Presentation: SUSP. Injection
Concentration: 1,000,000 U
Extended-release tablets: No
Made in: MEXICO