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Cuerpo Amarillo Fuerte 50 mg 6 AMPS 2 ml INJECTABLE, Progesteron

Cuerpo Amarillo Fuerte 50 mg 6 AMPS 2 ml INJECTABLE, Progesteron
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Cuerpo Amarillo Fuerte 50 mg 6 AMPS 2 ml INJECTABLE, Progesterona

INDICATIONS: Medication progestational treatment of disorders of the menstrual cycle (amenorrhea of ​​ovarian origin), functional bleeding without organic disorders manifest, threatened abortion.

Pharmacokinetics in Humans: Progesterone is produced in the ovary, the corpus luteum during the luteal phase of the menstrual cycle. It is responsible for developing a secretory endometrium during the luteal phase, the untimely decline of his release by the corpus luteum, is causing menstruation. Its mechanism of action has been described as stimulating the synthesis of proteins such as ovalbumin and avidin, as well as other proteins of the oviduct (mRNA synthesis).

Progesterone absorption is much more effective when applied intramuscularly that when administered orally. Progesterone absorption is rapid, so that its half-life is several minutes. And wide distribution in liver tissue is metabolized and conjugated with glucuronide (pregnanediol) and sulfate (pregnenolone) to be excreted. Approximately 10% of progesterone is excreted in urine as urinary pregnanediol and also removed 50 to 60% by feces.

A small amount of progesterone level is stored fat, but generally has no quantitative significance. Although removed rapidly when administered at daily intervals, reaches therapeutic effectiveness. The effects of progesterone in the body are still several days after the drug suspended.

The pharmacological effects of progesterone at higher therapeutic doses include suppression of ovulation inhibition of uterine contractility, increased excretion of sodium and negative nitrogen balance.

Hypersensitivity to the components of the formula. Vaginal bleeding or undiagnosed urinary tract, thrombophlebitis or thromboembolic disorders, malignant breast tumors undiagnosed cardiovascular disorders, abortion, pregnancy.

PRECAUTIONS: Prior to initiating therapy with progesterone should be performed in all women a physical examination with special attention to the breasts and pelvic organs and a Pap smear. Caution should be exercised YELLOW BODY STRONG ® (progesterone), with careful monitoring in those patients prone to fluid retention.

RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION: The use of progesterone during pregnancy or suspicion is contraindicated unless there is a medical judgment, circumstances in which the likely benefits outweigh the potential risks (eg, threatened abortion ). The use of progesterone during lactation is contraindicated.

SIDE EFFECTS: Nausea, dizziness, vomiting, dizziness, headache, weight gain or loss, intermenstrual bleeding, and occasionally may have depression or fatigue.

DRUG INTERACTIONS AND OTHER GENDER: It has been shown that phenytoin, phenobarbital and valproic acid can reduce the effectiveness of progesterone. Similarly, it has been reported that progesterone decreases the effect of rifampicin when administered concomitantly.

CHANGES IN RESULTS OF LABORATORY TESTS: Sometimes you can even modify the results of some laboratory tests such as thyroid function tests (for increased transcortin) test thyroxine-binding protein (tiroxinasa) curve glucose tolerance and determination of blood urea nitrogen.

PRECAUTIONS IN RELATION TO EFFECTS Carcinogenesis, Mutagenesis, Impairment of Fertility: In experimental animals at high doses has been observed breast nodules. However, in humans have not been reported such findings.

DOSAGE AND ADMINISTRATION: Intramuscular. From one to two ampoules per day (50 to 100 mg).

MANIFESTATIONS AND MANAGEMENT OF OVERDOSE OR ACCIDENTAL INGESTION: The acute toxicity of progesterone in animals is very low. With therapeutic purposes indicated, there are no reported cases of overdose.

PRESENTATION: Box with 6 ampoules of 2 ml.

RECOMMENDED STORAGE: Store at room temperature not exceeding 30 ° C. Protect from light.
  • Drug Name: Cuerpo Amarillo Fuerte
  • Comparable to:
  • Active Ingredients: Progesterone
  • Presentation: Injectable Solution
  • Concentration: 50mg
  • Prolonged release tablets: No
  • Laboratory GRIMANN, SA de CV
  • Box with 6 ampoules of 2ml
  • Made in Mexico

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